Ribosome

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Protein synthesis, translation (1)

Protein Synthesis, Translation Translation - the process of converting the mRNA codon sequences into an amino acid polypeptide chain. 1. Initiation - A ribosome attatches to the mRNA and starts to code at the FMet codon (usualy AUG, sometimes GUG or UUG). 2. Elongation - tRNA brings the corresponding amino acid to each codon as the ribosome moves down the mRNA strand. 3. Termination - Reading of the final mRNA codon (aka the STOP codon), which ends the sythesis of the peptide chain and releases it.
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Length: 00:01:42
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Ribosome in action

Nanotechnology at work
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Mrna translation (advanced)

The job of the mRNA is to carry the gene's message from the DNA out of the nucleus to a ribosome for production of the particular protein that this gene codes for. Originally created for DNA Interactive ( www.dnai.org ). TRANSCRIPT The job of this mRNA is to carry the genes message from the DNA out of the nuceus to a ribosome for production of the particular protein that this gene codes for. There can be several million ribosomes in a typical eukaryotic cell these complex catalytic machines use the mrna copy of the genetic information to assemble amino acid building blokes into the three dimensional proteins that are essential for life. Lets see how it works. The ribosome is composed of one large and one small sub-unit that assemble around the messenger RNA, which then passes through the ribosome like a computer tape. The amino acid building blocks (that's the small glowing red molecules) are carried into the ribosome attached to specific transfer RNAs. That's the larger green molecules also referred to as tRNA. The small sub-unit of the ribosome positions the mRNA so that it can be read in groups of three letters known as a codon. Each codon on the mRNA matches a corresponding anti-codon on the base of a transfer RNA molecule.The larger sub-unit of the ribosome removes each amino acid and join it onto the growing protein chain. As the mRNA is ratcheted through the ribosome, the mRNA sequence is translated into an amino acid sequence. There are three locations inside the ...
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Length: 00:02:18
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Ribosomes

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Ribosome and rna in protein synthesis

Our biology project on Protein synthesis and other organelles stuff: Ribosome goes on a quest to find his RNA, and gets stuck outside of the cell. OH NOES!
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Length: 00:05:25.500
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Ribosomes

Biology per 4
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Ribosome or ribozyme?

Chip Hunter and Tufan Gokirmak present the evidence that the ribosome is functioning as a catalytic unit in protein synthesis. The structure and catalytic properties of the rRNA are discussed, with emphasis on novel reagents and base-pair interactions. This presentation is the YouTube component of a graduate journal colloquium in Transformative Advances in Molecular Biology at the University of Florida. The course is part of the Horticultural Sciences Department and the Graduate Program in Plant Molecular and Cellular Biology and was led by Dr. Mark Settles and Dr. Kevin Folta.
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Length: 00:06:15
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Antibiotics targeting ribosomes: prof. ada yonath, nobel prize in chemistry 2009

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Length: 00:01:31.500
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Learn biology: cells—ribosomes

Learn Guitar FREE on iPhone & iPad: bit.ly Mahalo biology expert Mary Poffenroth tells you about the ribosomes of a cell. Ribosomes --------------------------------------------------------------------- Ribosomes are tiny structures floating in the cytoplasm or studded on the endoplasmic reticulum of a cell. They make proteins from amino acids. They are responsible for protein synthesis and even assemble some proteins. They are absolutely essential to healthy, functioning cells.c Read more by visiting our page at: www.mahalo.com
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Length: 00:00:54.750
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From structure and function of ribosomes to new antibiotics

Sterling Professor of Molecular Biophysics and Biochemistry, HHMI Investigator, and recipient of the 2009 Nobel Prize for Chemistry Thomas A. Steitz, Ph.D., gives his Nobel Lecture, which he first delivered at Stockholm University on December 8, two days before receiving the Nobel Prize from Swedens King Carl XVI Gustaf.
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Length: 00:38:18
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Metabolic melodies - "the ribosome"

Lyrics O beautiful with RNA To make the peptide bonds You hold t-RNA so it Can pair up with co-dons The Ribosome! The Ribosome! Translate mRNA Initiate and translocate From start to UGA A recording of Kevin Ahern's Metabolic Melodies. Also available for free download from www.davincipress.com
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Length: 00:00:35.250
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Biology: translation: ribosomal and transfer rna

www.mindbites.com for full video
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Length: 00:03:02.250
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Ribosome

A not so informative introduction to the ribosome.
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Length: 00:00:26.250
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Lecture by dr. ada yonath: the amazing ribosome, its tiny enemies and its origin

Ada Yonath, winner of the 2009 Nobel Prize in Chemistry, delivered a public lecture on Wednesday, April 7, 3:30 pm at New York Universitys Kimmel Center for University Life, NYC
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Length: 01:11:01.500
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Biology: signal peptides, er ribosomes

www.mindbites.com for full video
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Length: 00:01:33
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Bacterial ribosome translating rna into protein

This video is from Venki Ramakrishnan's group at the LMB in Cambridge, UK. It shows the ribosome in action, translating RNA into protein. Ramakrishnan won the 2009 Nobel prize for chemistry for his role in working out the structure and function of ribosomes. Find more videos and info at www.mrc-lmb.cam.ac.uk
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Length: 00:01:45.750
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Tata box inhibitors - ribosomal

taken from K7's longvideo "Kevin Saunderson - X-Mix 9 - Transmission From Deep Space Radio"
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The ribosome: the cell's protein-synthesizing machine and how antibiotics disrupt it

Determining the structure of the ribosome has made it possible for Ramakrishnan and his colleagues to image antibiotics bound to the ribosome, leading to a better understanding of their action, which could help in the development of novel drugs. In his talk, Ramakrishnan conveys the excitement in the field that has arisen as a result of these discoveries.
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Length: 00:07:06.750
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70s ribosome

The 70s Ribosome is made of two large subunits: the 30s and 50s. They, in turn are made of RNA and protein. The RNA is colored yellow, while the respective subunit proteins are colored different hues of blue. The tRNAs are colored purplish. Made in cinema 4D. The movement was keyed by Graham Johnson.
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Length: 00:00:08.250
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Ribosome-.wmv

Ribosomes are made of complex RNAs and proteins. Ribosomes are organelles in cells that make proteins or polypeptides from amino acids with instructions of mRNA from the cells nucleus. Protiens are used by the cell to carry out specific functions
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Length: 00:01:05.250
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Lec 5 - ribosomes

What are ribosomes exactly, and what's the difference between each type?
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Length: 00:02:14.250
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Interactive 3d ribosome

Ribosomes are organelles where proteins are synthesized. The consist of two thirds Ribosomal RNA (rRNA) and one third protein. Ribosomes build proteins from the genetic instructions within messenger RNA (mRNA). In this activity you will have a chance to view a ribosome up close and identify the different components involved in creating a protein chain. Then you will have a chance to try and beat the clock and label the components. Visit www.navtech3d.com for more information.
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Length: 00:00:31.500
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The ribosome: an infomercial

I edited this video for a Human Biology project.
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Length: 00:04:00.750
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Ribosome-translocon-membrane complex

The ribosome, protein factory for all cells, is seen in blue docked to the a protein-conducting channel, the tranlsocon, in gold. The translocon is in the process of inserting a new protein (green) into the membrane (white with red/blue/tan spheres), aided by a specific part of the ribosome in red. Membrane proteins play a key role in many human diseases, and understanding how they are inserted and then fold is critical to developing novel therapeutics targeting them. For more detail, see this site: www.ks.uiuc.edu Related paper: Jens Frauenfeld, James Gumbart, Eli O. van der Sluis, Soledad Funes, Marco Gartmann, Birgitta Beatrix, Thorsten Mielke, Otto Berninghausen, Thomas Becker, Klaus Schulten, and Roland Beckmann. Cryo-EM structure of the ribosome-SecYE complex in the membrane environment. Nature Structural & Molecular Biology, 2011. In press.
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Length: 00:00:26.250
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"how the ribosome ensures accuracy during decoding the genetic message"

Venki Ramakrishnan, PhD, Group Leader MRC Laboratory of Molecular Biology. The Fourth Annual Donald B. McCormick Lecture. Department of Biochemistry Emory University School of Medicine, Atlanta GA. Monday May 2, 2011.
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Length: 00:39:24
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Golgi apparatus & ribosomes

Mr Zhang Bergen County Academies Honors Biology Section 4 Golgi Apparatus & Ribosomes
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Length: 00:03:43.500
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Mrna translation (basic)

Originally created for DNA Interactive ( www.dnai.org ). TRANSCRIPT When the RNA copy is complete, it snakes out into the outer part of the cell. Then in a dazzling display of choreography, all the components of a molecular machine lock together around the RNA to form a miniature factory called a ribosome. It translates the genetic information in the RNA into a string of amino acids that will become a protein. Special transfer molecules, the green triangles, bring each amino acid to the ribosome. The amino acids are the small red tips attached to the transfer molecules. There are different transfer molecules for each of the twenty amino acids. Each transfer molecule carries a three letter code that is matched with the RNA in the machine. Now we come to the heart of the process. Inside the ribosome, the RNA is pulled through like a tape. The code for each amino acid is read off, three letters at a time, and matched to three corresponding letters on the transfer molecules. When the right transfer molecule plugs in, the amino acid it carries is added to the growing protein chain. Again, you are watching this in real time. And after a few seconds the assembled protein starts to emerge from the ribosome. Ribosomes can make any kind of protein. It just depends what genetic message you feed in on the RNA. In this case, the end product is hemoglobin. The cells in our bone marrow churn out a hundred trillion molecules of it per second! And as a result, our muscles, brain and all ...
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Length: 00:01:33.750
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Ef-tu delivers aminoacyl-trna to the ribosome

This shows the "decoding" step of protein synthesis
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Length: 00:01:14.250
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Prof. venkatraman ramakrishnan -- decoding by the ribosome

The Lokey Center Distinguished Lecture Series presents a lecture by Prof. Venkatraman Ramakrishnan of the Medical Research Council Laboratory of Molecular Biology, Cambridge, United Kingdom. Prof. Ramakrishnan is a 2009 Nobel Prize Laureate in Chemistry. Lecture title, "The Structural Basis of Decoding by the Ribosome". Lecture given March 3, 2011 in the Schulich Faculty of Chemistry.
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Length: 00:37:22.500
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Golgi apparatus & ribosomes

Mr Zhang Bergen County Academies Honors Biology Section 5 Golgi Apparatus & Ribosomes
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Length: 00:04:12.750
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Ribosomes commercial

What you need is ribosomes!
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Length: 00:01:31.500
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Ribosomes and the endoplasmic reticulum

My First Project
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Length: 00:03:10.500
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New protein exiting from a ribosome

Ribosome (in blue) makes cell proteins that then have to be moved or "translocated" by another protein, SecY (in gray, orange, yellow) across the cell membrane. The movie depicts the simulated translocation of a growing protein (in green) from the ribosomal exit tunnel into the channel of SecY. See here for more detail: www.ks.uiuc.edu Related paper: James Gumbart, Leonardo G. Trabuco, Eduard Schreiner, Elizabeth Villa, and Klaus Schulten. Regulation of the protein-conducting channel by a bound ribosome. Structure, 17:1453-1464, 2009. Link to article: tinyurl.com
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Length: 00:00:35.250
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Avoiding ribosome traffic jams

Optimization of protein synthesis for efficiency is thought to be highly important for evolutionary fitness. Watch and listen as Yitzhak Pilpel and Tamir Tuller take you on a brief, personalized tour of their findings that mRNA codons are distributed along the length of the message in a manner that modulates ribosome speed during translation. The ribosome "traffic pattern" generated by conserved codon distribution might minimize cellular energy expenditure.
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Length: 00:02:24.750
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Traduction sur ribosome

traduction de l'arn en protéine grace au ribosome dans le noyau d'une cellule eucaryote
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Golgi apparatus & ribosomes

Mr Zhang Bergen County Academies Honors Biology Section 6 Golgi Apparatus & Ribosomes
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Length: 00:03:01.500
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Ribosomes

RIbosomes
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Ribosomes by adriana garcia

This is my science project about ribosomes, I hope I get an A
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Length: 00:00:54
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Golgi apparatus & ribosomes

Mr Zhang Bergen County Academies Honors Biology Section 2 Golgi Apparatus & Ribosomes
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Length: 00:01:48.750
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Ribosome ratchet

The ratchet-like rearrangements at the interface between two ribosomal subunits may help move the mRNA and tRNAs through the ribosome during protein synthesis. This video is from: Essential Cell Biology, 3rd Edition Alberts, Bray, Hopkin, Johnson, Lewis, Raff, Roberts, & Walter ISBN: 978-0-8153-4129-1
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Length: 00:00:44.250
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The amazing ribosome: its tiny enemies and its origin, pt. 1

NYU Chemistry is pleased to welcome Nobel Laureate Ada E. Yonath, the Martin S. and Helen Kimmel Professor of Structural Biology at the Weizmann Institute in Israel, who will deliver a seminar on April 7, 2010.
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Length: 00:17:45.750
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Ribosome by sharkattack

ribosome by sharkattack
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Length: 00:01:00.750
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Ribosome golgi body lysosome cell organelle by siddharth sanghvi sir wxyz.in 0731.in mp09.com

ribosome golgi body lysosome cell organelle by siddharth sanghvi sir wxyz.in 0731.in mp09.com aipmt aiims jipmer bhu mppmt rpmt upmt medical entrance examination ias ips botany civil services
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Length: 00:50:10.500
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Belly dancing ribosome

This is a Normal Mode Simulation of a ribosome (30 S part is removed) together with a transfer RNA. From the work of Jernigan & Bahar: "Global Ribosome Motions Revealed with Elastic Network Model" Wang, Y. Rader, AJ, Bahar, I. & Jernigan, RL. , J. Struct Biol 147: 302-314, 2004. Soundtrack: İkimiz bir fidanız-Hakkı Bulut
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Length: 00:00:21
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Ribosome rotation with large subunit fade away

I've tangled with the amazing ribosome structure published by the Steitz lab (large subunit 1ffk.pdb), and the Yonath and Ramakrishnan labs (small subunit, 1fja.pdb and 1fjg.pdb respectively) since the first edition of our textbook in 2000. Since that time, and all atoms model generated with other hybrid techniques has been published. In honor of the nobel effort, I'm posting a handful of simple rotation movies that show the basic anatomy of the whole ribosome. Here we see the large subunit generated from the original Steitz data 1ffk and other models as an all atoms model 1twv sitting on top of the small subunit, 1twt. The Large 50s subunit consisting of the 23s (dark red) and 5s (bright red) RNAs along with the associated ribosomal proteins (dark purple), fades away on the second rotation to reveal the complementary face of the 30s subunit which in this file contains the 16s RNA (pink), the associated proteins, two tRNAs (orange) bound to a bright yellow mRNA which is buried too deep in the active site to see since its only 2 bases long. (Actually, the large subunit fades in on the second rotation... I thought I could make Youtube loop this infinitely, but can't figure out how.)
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Length: 00:00:08.250
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16s ribosomal small subunit rap

Bil explains the Human Microbiome Project in verse at the Toastmasters 2011 International Convention
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Length: 00:03:04.500
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Molecular modeling of the ribosome during translocation via mdfit

This video shows how atomic models of the ribosome are made with MDfit: a method that integrates molecular simulations and cryogenic electron microscopy. This video depicts the preparation of models of hybrid configurations of the P-site tRNA inside of the ribosome. The final models are described in Ratje et al. "Head swivel on the ribosome facilitates translocation via intra-subunit tRNA hybrid sites." Nature 468, 713-716, 2010. These fits were performed on the NMCAC Encanto Supercomputer. For more information on the modeling, see smog.ucsd.edu
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Length: 00:00:30
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